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Query: SPIRE2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SPIRE2 1 3.867 -1.600 2.860 1.007

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SPIRE2:


Pubmed-SPIRE2 »
Uniprot-SPIRE2 »
Biogrid-SPIRE2 »
ProteomicsDB-SPIRE2 »

Tumorportal-SPIRE2 »
COSMIC-SPIRE2 »
GenomeRNAi-SPIRE2 »
Genecards-SPIRE2


Protein-protein Interactions for SPIRE2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXW11 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF11 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPIRE2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait BCL7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMOD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SPIRE2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members KIND IPR011019 0.13


Protein complexes (CORUM database) featuring SPIRE2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SPIRE2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0046907 intracellular transport Database 3.25
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0032154 cleavage furrow Database 2.01
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0040038 polar body extrusion after meiotic divisions Database 0.74
Category members GO Category GO:0051295 establishment of meiotic spindle localization Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0070649 formin-nucleated actin cable assembly Database 0.39
Category members GO Category GO:0036089 cleavage furrow formation Database 0.09
Category members Pathway Pathway_1073 KEGG_DORSO_VENTRAL_AXIS_FORMATION 0 0


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