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Query: SNRNP200

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNRNP200 2 8.340 -2.430 4.430 0.929 -0.475 -0.147 -0.376 0.060

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SNRNP200 Ubiquitylation K557 1.715 _SLVQEMVGSFGK(gl)R_
SNRNP200 Ubiquitylation K479 0.256 1.664 _YAQAGFEGFK(gl)TLNR_
SNRNP200 Ubiquitylation K487 1.596 _IQSK(gl)LYR_
SNRNP200 Ubiquitylation K284 -0.370 1.144 _FYDDAIVSQK(gl)K_
SNRNP200 Ubiquitylation K2080 0.670 0.568 _SNSLISIK(gl)R_
SNRNP200 Phosphorylation S225 0.540 0.498 _EEAS(ph)DDDMEGDEAVVR_
SNRNP200 Ubiquitylation K2087 0.252 _LTLQQK(gl)AK_
SNRNP200 Ubiquitylation K2089 1.167 0.252 _LTLQQKAK(gl)_
SNRNP200 Ubiquitylation K1544 -0.229 -0.207 _LLSMAK(gl)PVYHAITK_
SNRNP200 Ubiquitylation K770 0.795 _TEAEQCK(gl)NLELK_

Background Information for SNRNP200:





Protein-protein Interactions for SNRNP200

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCAS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait CRNKL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait FERMT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PQBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPF4 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB4B Cat. description Hein, Mann, Cell 2015
Category members IP bait SART1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait SNW1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C20orf4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C2orf3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD2BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAPP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ECD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPBP1L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1143 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP40 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSSC4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNRNP200

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Sec63-dom IPR004179 0.85
Category members Helicase/UvrB_dom IPR006935 0.78
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35


Protein complexes (CORUM database) featuring SNRNP200

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1335 SNW1 complex Database 3.59
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring SNRNP200

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0005682 U5 snRNP Database 0.57
Category members GO Category GO:0019013 viral nucleocapsid Database 0.55
Category members GO Category GO:0000354 cis assembly of pre-catalytic spliceosome Database 0.32
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members Disease phenotype Retinitis_pigmentosa Retinitis pigmentosa Database 0


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