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Query: SMU1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMU1 2 6.129 -2.320 4.100 -0.497 -0.559 0.627 -0.536 -0.034
SMU1 2 6.129 -0.600 0.320 -0.497 -0.559 0.627 -0.536 -0.034

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMU1 Ubiquitylation K379 2.016 0.354 _IWNMK(gl)TTECSNTFK_
SMU1 Ubiquitylation K214 1.900 0.288 _FGQK(gl)SHVECAR_
SMU1 Ubiquitylation K287 -0.282 _DTEMLATGAQDGK(gl)IK_
SMU1 Ubiquitylation K289 -0.282 _DTEMLATGAQDGK(gl)IK_
SMU1 Ubiquitylation K194 1.054 _AAVK(gl)DVEEEKFPTQLSR_
SMU1 Ubiquitylation K308 2.674 _AHSK(gl)GVTCLSFSK_
SMU1 Ubiquitylation K337 2.033 _IHGLK(gl)SGK_
SMU1 Ubiquitylation K340 1.885 _IHGLKSGK(gl)_

Background Information for SMU1:


Pubmed-SMU1 »
Uniprot-SMU1 »
Biogrid-SMU1 »
ProteomicsDB-SMU1 »

Tumorportal-SMU1 »
COSMIC-SMU1 »
GenomeRNAi-SMU1 »
Genecards-SMU1


Protein-protein Interactions for SMU1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PQBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait SMU1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SMU1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members Nucleoporin_Nup160 IPR021717 0.35
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members LisH_dimerisation IPR006594 0.06
Category members CTLH_C IPR006595 0


Protein complexes (CORUM database) featuring SMU1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring SMU1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6


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