bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SMG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMG1 1 3.258 -0.880 0.740 1.025 -0.011 -0.624
SMG1 1 3.258 -0.040 -0.310 1.025 -0.011 -0.624

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMG1 Phosphorylation T3574 2.128 _NLATSADT(ph)PPSTVPGTGK_

Background Information for SMG1:


Pubmed-SMG1 »
Uniprot-SMG1 »
Biogrid-SMG1 »
ProteomicsDB-SMG1 »

Tumorportal-SMG1 »
COSMIC-SMG1 »
GenomeRNAi-SMG1 »
Genecards-SMG1


Protein-protein Interactions for SMG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HSP90B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMG9 Cat. description Hein, Mann, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SMG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members PI3/4_kinase_cat_dom IPR000403 1.52
Category members FATC IPR003152 0.68
Category members PIK_FAT IPR014009 0.68
Category members Kinase-like_dom IPR011009 0.03


Protein complexes (CORUM database) featuring SMG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 784 SMG-1-Upf1-eRF1-eRF3 complex (SURF) Database 0.08


Categories featuring SMG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0046854 phosphatidylinositol phosphorylation Database 0.31
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0018105 peptidyl-serine phosphorylation Database 0.18
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


.

© Copyright Svejstrup Laboratory 2015