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Query: SMCHD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMCHD1 0 0.393 -0.025 -0.104 -0.042 0.384 0.295

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMCHD1 Ubiquitylation K812 -0.365 -0.476 _LQVVLNESNADTYAGRPLPSK(gl)AIK_
SMCHD1 Ubiquitylation K1374 0.361 _LNVK(gl)YDK_

Background Information for SMCHD1:


Pubmed-SMCHD1 »
Uniprot-SMCHD1 »
Biogrid-SMCHD1 »
ProteomicsDB-SMCHD1 »

Tumorportal-SMCHD1 »
COSMIC-SMCHD1 »
GenomeRNAi-SMCHD1 »
Genecards-SMCHD1


Protein-protein Interactions for SMCHD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRCA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait GNPNAT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRIF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NDC80 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMCHD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRPC4AP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SMCHD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HATPase_C IPR003594 1.07
Category members SMC_hinge IPR010935 0


Protein complexes (CORUM database) featuring SMCHD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SMCHD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0051276 chromosome organization Database 0.1
Category members GO Category GO:0001740 Barr body Database 0.03
Category members GO Category GO:0009048 dosage compensation by inactivation of X chromosome Database 0


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