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Query: SLIT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLIT1 0 -3.558 0.990 -0.510 -3.112 -1.071

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLIT1 Ubiquitylation K103 0.625 _GAFQDLK(gl)ELER_
SLIT1 Ubiquitylation K825 0.073 _TFDGLK(gl)SLR_
SLIT1 Ubiquitylation K72 -1.544 _ITK(gl)TDFAGLR_

Background Information for SLIT1:


Pubmed-SLIT1 »
Uniprot-SLIT1 »
Biogrid-SLIT1 »
ProteomicsDB-SLIT1 »

Tumorportal-SLIT1 »
COSMIC-SLIT1 »
GenomeRNAi-SLIT1 »
Genecards-SLIT1


Protein-protein Interactions for SLIT1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SLIT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EG-like_dom IPR000742 1.74
Category members EGF-like_Ca-bd_dom IPR001881 0.69
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members Leu-rich_rpt IPR001611 0.32
Category members Cys-rich_flank_reg_C IPR000483 0.21
Category members LRR-contain_N IPR000372 0.13
Category members Laminin_G IPR001791 0.06
Category members Cys_knot_C IPR006207 0.03
Category members Fol_N IPR003645 0.01
Category members ConA-like_lec_gl_sf IPR008985 0


Protein complexes (CORUM database) featuring SLIT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLIT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005615 extracellular space Database 4.72
Category members Pathway Pathway_673 REACTOME_AXON_GUIDANCE 0 1.06
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_294 PID_AJDISS_2PATHWAY 0 0.18
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0022029 telencephalon cell migration Database 0.11
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0021772 olfactory bulb development Database 0.06
Category members GO Category GO:0048846 axon extension involved in axon guidance Database 0.05
Category members GO Category GO:0048853 forebrain morphogenesis Database 0.04
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members Pathway Pathway_692 REACTOME_NETRIN1_SIGNALING 0 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0008045 motor neuron axon guidance Database 0
Category members GO Category GO:0021510 spinal cord development Database 0
Category members GO Category GO:0022028 tangential migration from the subventricular zone to the olfactory bulb Database 0
Category members GO Category GO:0031290 retinal ganglion cell axon guidance Database 0
Category members GO Category GO:0033563 dorsal/ventral axon guidance Database 0
Category members GO Category GO:0040023 establishment of nucleus localization Database 0
Category members GO Category GO:0043395 heparan sulfate proteoglycan binding Database 0
Category members GO Category GO:0048495 Roundabout binding Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0048843 negative regulation of axon extension involved in axon guidance Database 0
Category members GO Category GO:0050919 negative chemotaxis Database 0
Category members GO Category GO:0051964 negative regulation of synapse assembly Database 0


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