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Query: SLC16A1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC16A1 1 5.213 -0.560 0.200 0.052 0.242
SLC16A1 1 5.213 -0.560 0.200 0.565 -1.615 -0.618

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC16A1 Ubiquitylation K196 1.643 1.317 _SK(gl)ASLEK(gl)AGK_
SLC16A1 Ubiquitylation K204 1.669 0.701 _K(gl)DLHDANTDLIGR_
SLC16A1 Phosphorylation S447 0.593 0.575 _EEETS(ph)IDVAGKPNEVTK_
SLC16A1 Phosphorylation S441 0.146 0.548 _ES(ph)KEEETSIDVAGKPNEVTK_
SLC16A1 Phosphorylation T446 -0.042 0.522 _EEET(ph)SIDVAGKPNEVTK_
SLC16A1 Phosphorylation S483 0.251 0.140 _AAES(ph)PDQKDTDGGPKEEESPV_
SLC16A1 Ubiquitylation K453 0.905 -0.086 _ESKEEETSIDVAGK(gl)PNEVTK_
SLC16A1 Phosphorylation S498 -0.205 -0.098 _DTDGGPKEEES(ph)PV_
SLC16A1 Phosphorylation S463 -0.317 -0.135 _AAES(ph)PDQKDTEGGPKEEESPV_
SLC16A1 Phosphorylation S478 -0.316 -0.157 _DTEGGPKEEES(ph)PV_
SLC16A1 Ubiquitylation K467 -0.697 _AAESPDQK(gl)DTEGGPKEEESPV_
SLC16A1 Ubiquitylation K474 -1.372 _AAESPDQKDTEGGPK(gl)EEESPV_
SLC16A1 Ubiquitylation K487 -2.206 _AAESPDQK(gl)DTDGGPKEEESPV_
SLC16A1 Ubiquitylation K494 -2.206 _AAESPDQK(gl)DTDGGPKEEESPV_
SLC16A1 Ubiquitylation K191 1.643 _SK(gl)ASLEK(gl)AGK_
SLC16A1 Ubiquitylation K203 1.190 _SGVK(gl)KDLHDANTDLIGR_
SLC16A1 Ubiquitylation K442 0.797 _ESK(gl)EEETSIDVAGKPNEVTK_
SLC16A1 Ubiquitylation K459 -0.015 _ESKEEETSIDVAGKPNEVTK(gl)AAESPDQK_

Background Information for SLC16A1:


Pubmed-SLC16A1 »
Uniprot-SLC16A1 »
Biogrid-SLC16A1 »
ProteomicsDB-SLC16A1 »

Tumorportal-SLC16A1 »
COSMIC-SLC16A1 »
GenomeRNAi-SLC16A1 »
Genecards-SLC16A1


Protein-protein Interactions for SLC16A1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM46A Cat. description Hein, Mann, Cell 2015
Category members IP bait MAP3K12 Cat. description Hein, Mann, Cell 2015


Protein Domains in SLC16A1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Monocarb_transpt IPR004743 0.05
Category members MFS IPR011701 0
Category members MFS_dom_general_subst_transpt IPR016196 0
Category members MFS_dom IPR020846 0


Protein complexes (CORUM database) featuring SLC16A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC16A1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_14 REACTOME_PYRUVATE_METABOLISM 0 0.05
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0015355 secondary active monocarboxylate transmembrane transporter activity Database 0.05
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0006090 pyruvate metabolic process Database 0.04
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members Pathway Pathway_927 REACTOME_BASIGIN_INTERACTIONS 0 0
Category members Pathway Pathway_1316 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS 0 0
Category members Pathway Pathway_750 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 0 0
Category members GO Category GO:0008028 monocarboxylic acid transmembrane transporter activity Database 0
Category members GO Category GO:0015293 symporter activity Database 0
Category members GO Category GO:0015711 organic anion transport Database 0
Category members GO Category GO:0015718 monocarboxylic acid transport Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0071407 cellular response to organic cyclic compound Database 0


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