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bioLOGIC Data

Query: SLBP

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
SLBP	0	0.903	-0.370	0.950

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
SLBP	Phosphorylation	S254		0.730	_HMDS(ph)QVEDEFDLEACLTEPLRDFSAMS_
SLBP	Phosphorylation	S7	-0.777	-0.205	_(ac)ACRPRS(ph)PPR_
SLBP	Phosphorylation	S59		-1.062	_RPES(ph)FTTPEGPKPR_
SLBP	Phosphorylation	T62	-1.930	-2.227	_RPESFTT(ph)PEGPKPR_

Background Information for SLBP:

Pubmed-SLBP »

Uniprot-SLBP »

Biogrid-SLBP »

ProteomicsDB-SLBP »

Tumorportal-SLBP »

COSMIC-SLBP »

GenomeRNAi-SLBP »

Genecards-SLBP

Protein-protein Interactions for SLBP

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait TACC3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait GSTM3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait P4HA3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZFC3H1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in SLBP

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring SLBP

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring SLBP

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0005654	nucleoplasm	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0010467	gene expression	Database	INF
Category members	Pathway	Pathway_373	REACTOME_MRNA_PROCESSING	0	12.92
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	Pathway	Pathway_380	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	0	12.24
Category members	Pathway	Pathway_348	REACTOME_TRANSCRIPTION	0	9
Category members	GO Category	GO:0030529	ribonucleoprotein complex	Database	8.45
Category members	Pathway	Pathway_878	REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM	0	6.53
Category members	GO Category	GO:0006406	mRNA export from nucleus	Database	4.09
Category members	Pathway	Pathway_375	REACTOME_RNA_POL_II_TRANSCRIPTION	0	2.46
Category members	GO Category	GO:0051028	mRNA transport	Database	1.7
Category members	GO Category	GO:0003729	mRNA binding	Database	1.38
Category members	GO Category	GO:0006366	transcription from RNA polymerase II promoter	Database	0.96
Category members	Pathway	Pathway_854	REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_	0	0.91
Category members	GO Category	GO:0031124	mRNA 3'-end processing	Database	0.91
Category members	GO Category	GO:0006369	termination of RNA polymerase II transcription	Database	0.87
Category members	Pathway	Pathway_853	REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA	0	0.05
Category members	Pathway	Pathway_885	REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS	0	0
Category members	GO Category	GO:0006398	histone mRNA 3'-end processing	Database	0
Category members	GO Category	GO:0008334	histone mRNA metabolic process	Database	0
Category members	GO Category	GO:0033260	nuclear cell cycle DNA replication	Database	0
Category members	GO Category	GO:0071204	histone pre-mRNA 3'end processing complex	Database	0
Category members	GO Category	GO:0071207	histone pre-mRNA stem-loop binding	Database	0
Category members	GO Category	GO:0071208	histone pre-mRNA DCP binding	Database	0