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Query: SIPA1L1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SIPA1L1 1 3.994 -0.260 0.030
SIPA1L1 1 3.994 -0.260 0.030 0.397 0.037 -0.084

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SIPA1L1 Ubiquitylation K1515 1.582 _STIEDDLK(gl)K_
SIPA1L1 Ubiquitylation K1516 1.582 _STIEDDLK(gl)K_
SIPA1L1 Phosphorylation S1544 0.985 1.047 _TLS(ph)DESLCSGR_
SIPA1L1 Phosphorylation S1585 0.556 0.584 _TLS(ph)DESIYNSQR_
SIPA1L1 Phosphorylation S1528 0.028 0.107 _DLRAS(ph)PKPTSK_
SIPA1L1 Phosphorylation S1549 0.247 -0.092 _LIDLES(ph)PTPESQK_
SIPA1L1 Phosphorylation S162 -0.151 _FLMPEAYPS(ph)SPRK_
SIPA1L1 Phosphorylation S1364 -0.112 -0.154 _EVS(ph)PAPAVAGQSK_
SIPA1L1 Phosphorylation T1705 -0.178 _TTPT(ph)MSEEPPLDLTGK_
SIPA1L1 Phosphorylation T1703 -0.192 _TT(ph)PTMSEEPPLDLTGK_
SIPA1L1 Phosphorylation S1433 0.276 -0.282 _HSAS(ph)PVVFTSAR_
SIPA1L1 Phosphorylation S161 -0.617 _FLMPEAYPS(ph)SPRK_
SIPA1L1 Phosphorylation T1702 -0.665 _T(ph)TPTM(ox)SEEPPLDLTGK_

Background Information for SIPA1L1:


Pubmed-SIPA1L1 »
Uniprot-SIPA1L1 »
Biogrid-SIPA1L1 »
ProteomicsDB-SIPA1L1 »

Tumorportal-SIPA1L1 »
COSMIC-SIPA1L1 »
GenomeRNAi-SIPA1L1 »
Genecards-SIPA1L1


Protein-protein Interactions for SIPA1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait FLOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IQGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLF1IP Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO19 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNPO Cat. description Hein, Mann, Cell 2015
Category members IP bait FKBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAMBPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SIPA1L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15
Category members Rap_GAP_dom IPR000331 0.02
Category members DUF3401 IPR021818 0


Protein complexes (CORUM database) featuring SIPA1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SIPA1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043197 dendritic spine Database 0.86
Category members GO Category GO:0046875 ephrin receptor binding Database 0.3
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0061001 regulation of dendritic spine morphogenesis Database 0.23
Category members GO Category GO:0005096 GTPase activator activity Database 0.19
Category members GO Category GO:0048167 regulation of synaptic plasticity Database 0.14
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0032317 regulation of Rap GTPase activity Database 0
Category members GO Category GO:0032861 activation of Rap GTPase activity Database 0
Category members GO Category GO:0048013 ephrin receptor signaling pathway Database 0
Category members GO Category GO:0050770 regulation of axonogenesis Database 0


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