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Query: SIM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SIM1 0 -0.897 -0.140 -0.520

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SIM1 Ubiquitylation K51 -0.897 _LTTSYLK(gl)MR_

Background Information for SIM1:


Pubmed-SIM1 »
Uniprot-SIM1 »
Biogrid-SIM1 »
ProteomicsDB-SIM1 »

Tumorportal-SIM1 »
COSMIC-SIM1 »
GenomeRNAi-SIM1 »
Genecards-SIM1


Protein-protein Interactions for SIM1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SIM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PAS_fold_3 IPR013655 0.69
Category members bHLH_dom IPR011598 0.32
Category members PAS_fold IPR013767 0.27
Category members PAC IPR001610 0.23
Category members PAS IPR000014 0.23
Category members SIM_C IPR010578 0.18


Protein complexes (CORUM database) featuring SIM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SIM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0001657 ureteric bud development Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0


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