bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SET

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SET 0 5.608 -0.480 0.260
SET 0 5.608 -0.480 0.260 0.464 0.554 0.204 0.186

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SET Phosphorylation S5 0.974 1.416 _(ac)M(ox)PRS(ph)HQPPPPPHEKEQQEAIEHIDEVQNEIDR_
SET Ubiquitylation K132 0.135 1.415 _VEVTEFEDIK(gl)SGYR_
SET Phosphorylation S50 0.839 0.970 _LNEQAS(ph)EEILK_
SET Ubiquitylation K172 -0.135 0.904 _STEIK(gl)WK_
SET Ubiquitylation K68 0.085 0.780 _LNEQASEEILK(gl)VEQK_
SET Ubiquitylation K154 0.022 0.406 _VLSK(gl)EFHLNESGDPSSK_
SET Ubiquitylation K83 -0.051 0.259 _QPFFQK(gl)R_
SET Ubiquitylation K167 -0.264 -0.069 _EFHLNESGDPSSK(gl)STEIK_
SET Phosphorylation S7 -0.663 -0.220 _RQS(ph)PLPPQK_

Background Information for SET:


Pubmed-SET »
Uniprot-SET »
Biogrid-SET »
ProteomicsDB-SET »

Tumorportal-SET »
COSMIC-SET »
GenomeRNAi-SET »
Genecards-SET


Protein-protein Interactions for SET
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait JARID1C;KDM5C Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2CB Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP2R1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SET Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPATS2L Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SET
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NAP_family IPR002164 0


Protein complexes (CORUM database) featuring SET
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5153 CTFC-TAF1 complex Database 0


Categories featuring SET
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members GO Category GO:0006260 DNA replication Database 3.34
Category members GO Category GO:0006337 nucleosome disassembly Database 3
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0035067 negative regulation of histone acetylation Database 0.08
Category members Pathway Pathway_291 BIOCARTA_SET_PATHWAY 0 0.04
Category members GO Category GO:0004864 protein phosphatase inhibitor activity Database 0
Category members GO Category GO:0008601 protein phosphatase type 2A regulator activity Database 0


.

© Copyright Svejstrup Laboratory 2015