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Query: SENP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SENP2 0 2.460 -0.290 0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SENP2 Phosphorylation S107 0.949 0.929 _RRS(ph)DSTLFSTVDTDEIPAK_
SENP2 Phosphorylation S419 1.231 0.883 _KVS(ph)IIETK_

Background Information for SENP2:


Pubmed-SENP2 »
Uniprot-SENP2 »
Biogrid-SENP2 »
ProteomicsDB-SENP2 »

Tumorportal-SENP2 »
COSMIC-SENP2 »
GenomeRNAi-SENP2 »
Genecards-SENP2


Protein-protein Interactions for SENP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DENND6A Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait SENP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SENP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_C48 IPR003653 0


Protein complexes (CORUM database) featuring SENP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SENP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members GO Category GO:0019904 protein domain specific binding Database 1.85
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0016605 PML body Database 1.41
Category members Pathway Pathway_840 ST_WNT_BETA_CATENIN_PATHWAY 0 0.6
Category members GO Category GO:0060712 spongiotrophoblast layer development Database 0.45
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members GO Category GO:0001934 positive regulation of protein phosphorylation Database 0.22
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0030111 regulation of Wnt signaling pathway Database 0.08
Category members GO Category GO:0032091 negative regulation of protein binding Database 0.08
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members Pathway Pathway_290 WNT_SIGNALING 0 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0009950 dorsal/ventral axis specification Database 0
Category members GO Category GO:0016926 protein desumoylation Database 0
Category members GO Category GO:0016929 SUMO-specific protease activity Database 0
Category members GO Category GO:0035562 negative regulation of chromatin binding Database 0
Category members GO Category GO:0051246 regulation of protein metabolic process Database 0
Category members GO Category GO:0060707 trophoblast giant cell differentiation Database 0
Category members GO Category GO:0060711 labyrinthine layer development Database 0


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