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Query: SEC62

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SEC62 1 5.425 0.680 -0.300 1.850 0.588 0.566

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SEC62 Ubiquitylation K65 1.149 1.308 _AK(gl)KGEEALFTTR_
SEC62 Ubiquitylation K26 0.519 0.921 _AVAK(gl)YLR_
SEC62 Ubiquitylation K19 0.553 0.063 _IQEVGEPSK(gl)EEK_
SEC62 Phosphorylation T375 0.112 -0.148 _EELEQQT(ph)DGDCEEDEEEENDGETPK_
SEC62 Ubiquitylation K22 0.368 _RIQEVGEPSKEEK(gl)_
SEC62 Ubiquitylation K35 0.603 _FNCPTK(gl)STNMMGHR_
SEC62 Ubiquitylation K60 0.986 _AVDCLLDSK(gl)WAK_
SEC62 Ubiquitylation K66 0.507 _K(gl)GEEALFTTR_

Background Information for SEC62:


Pubmed-SEC62 »
Uniprot-SEC62 »
Biogrid-SEC62 »
ProteomicsDB-SEC62 »

Tumorportal-SEC62 »
COSMIC-SEC62 »
GenomeRNAi-SEC62 »
Genecards-SEC62


Protein-protein Interactions for SEC62
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYH7B Cat. description Hein, Mann, Cell 2015
Category members IP bait RAPGEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TBC1D9B Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM132A Cat. description Hein, Mann, Cell 2015
Category members IP bait B3GNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GYPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNK16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SEC62
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ABC1_TM_dom IPR011527 0.33


Protein complexes (CORUM database) featuring SEC62
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SEC62
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0006620 posttranslational protein targeting to membrane Database 0.93
Category members Pathway Pathway_914 KEGG_PROTEIN_EXPORT 0 0.7
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0006613 cotranslational protein targeting to membrane Database 0.31
Category members GO Category GO:0008565 protein transporter activity Database 0.26
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0042626 ATPase activity, coupled to transmembrane movement of substances Database 0.09
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0016235 aggresome Database 0


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