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Query: SEC11A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SEC11A 0 3.768 0.080 -0.570
SEC11A 0 3.768 0.080 -0.570 1.439 0.787 0.419

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SEC11A Ubiquitylation K109 1.123 _VLK(gl)IHEK_
SEC11A Ubiquitylation K123 -1.452 0.393 _FLTK(gl)GDNNAVDDR_

Background Information for SEC11A:


Pubmed-SEC11A »
Uniprot-SEC11A »
Biogrid-SEC11A »
ProteomicsDB-SEC11A »

Tumorportal-SEC11A »
COSMIC-SEC11A »
GenomeRNAi-SEC11A »
Genecards-SEC11A


Protein-protein Interactions for SEC11A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GPC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SEC11A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peptidase_S26B IPR001733 0.15
Category members Peptidase_S24_S26A/B/C IPR015927 0
Category members Peptidase_S24_S26 IPR019759 0


Protein complexes (CORUM database) featuring SEC11A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SEC11A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members Pathway Pathway_459 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 0 INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006614 SRP-dependent cotranslational protein targeting to membrane Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members Pathway Pathway_5 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM 0 0.9
Category members Pathway Pathway_914 KEGG_PROTEIN_EXPORT 0 0.7
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members Pathway Pathway_270 REACTOME_REGULATION_OF_INSULIN_SECRETION 0 0.09
Category members GO Category GO:0050796 regulation of insulin secretion Database 0.06
Category members GO Category GO:0008233 peptidase activity Database 0.02
Category members Pathway Pathway_731 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN 0 0
Category members Pathway Pathway_917 REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION 0 0
Category members Pathway Pathway_918 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 0 0
Category members Pathway Pathway_919 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP 0 0
Category members GO Category GO:0006465 signal peptide processing Database 0
Category members GO Category GO:0006508 proteolysis Database 0
Category members GO Category GO:0008236 serine-type peptidase activity Database 0


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