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Query: SCP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCP2 0 2.347 -1.130 1.900 0.119 -0.044 -0.048

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SCP2 Ubiquitylation K438 0.328 _ANLVFK(gl)EIEK_
SCP2 Ubiquitylation K454 0.420 _KLEEEGEQFVKK(gl)_
SCP2 Ubiquitylation K462 -0.147 _IGGIFAFK(gl)_

Background Information for SCP2:


Pubmed-SCP2 »
Uniprot-SCP2 »
Biogrid-SCP2 »
ProteomicsDB-SCP2 »

Tumorportal-SCP2 »
COSMIC-SCP2 »
GenomeRNAi-SCP2 »
Genecards-SCP2


Protein-protein Interactions for SCP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SCP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SCP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Thiolase-like IPR016039 0.26
Category members SCP2_sterol-bd_dom IPR003033 0.04
Category members Thiolase IPR002155 0
Category members Ketoacyl_synth_N IPR014030 0
Category members Thiolase_N IPR020616 0
Category members Thiolase_C IPR020617 0


Protein complexes (CORUM database) featuring SCP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SCP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups Database 0.33
Category members GO Category GO:0006694 steroid biosynthetic process Database 0.29
Category members GO Category GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase Database 0.23
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members Pathway Pathway_143 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM 0 0.07
Category members GO Category GO:0033559 unsaturated fatty acid metabolic process Database 0.07
Category members GO Category GO:0036109 alpha-linolenic acid metabolic process Database 0.07
Category members Pathway Pathway_26 REACTOME_PEROXISOMAL_LIPID_METABOLISM 0 0.04
Category members GO Category GO:0015485 cholesterol binding Database 0.04
Category members GO Category GO:0032934 sterol binding Database 0.04
Category members GO Category GO:0008526 phosphatidylinositol transporter activity Database 0.02
Category members Pathway Pathway_167 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL 0 0
Category members Pathway Pathway_168 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM 0 0
Category members Pathway Pathway_169 KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_170 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS 0 0
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000062 fatty-acyl-CoA binding Database 0
Category members GO Category GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006633 fatty acid biosynthetic process Database 0
Category members GO Category GO:0006699 bile acid biosynthetic process Database 0
Category members GO Category GO:0006701 progesterone biosynthetic process Database 0
Category members GO Category GO:0006869 lipid transport Database 0
Category members GO Category GO:0007031 peroxisome organization Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008206 bile acid metabolic process Database 0
Category members GO Category GO:0015914 phospholipid transport Database 0
Category members GO Category GO:0032959 inositol trisphosphate biosynthetic process Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0


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