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Query: SCARB2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCARB2 0 1.791 0.220 0.470 0.565 0.756

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SCARB2:


Pubmed-SCARB2 »
Uniprot-SCARB2 »
Biogrid-SCARB2 »
ProteomicsDB-SCARB2 »

Tumorportal-SCARB2 »
COSMIC-SCARB2 »
GenomeRNAi-SCARB2 »
Genecards-SCARB2


Protein-protein Interactions for SCARB2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SCARB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB27B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RHCG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCARB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SCARB2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members CD36 IPR002159 0.21
Category members CD36_antigen IPR005428 0.21


Protein complexes (CORUM database) featuring SCARB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SCARB2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016020 membrane Database 0.52
Category members Disease phenotype Gaucher_disease_type_1 Gaucher disease type 1 Database 0.21
Category members GO Category GO:0043202 lysosomal lumen Database 0.07
Category members GO Category GO:0006622 protein targeting to lysosome Database 0.02
Category members Pathway Pathway_74 KEGG_LYSOSOME 0 0
Category members Disease phenotype Unverricht-Lundborg_disease Unverricht-Lundborg disease Database 0
Category members GO Category GO:0004872 receptor activity Database 0
Category members GO Category GO:0005764 lysosome Database 0
Category members GO Category GO:0007155 cell adhesion Database 0


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