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Query: SCAF8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCAF8 3 5.736 -0.040 0.020 2.902 -1.906 1.881 -0.403 0.132

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SCAF8 Phosphorylation S695 -0.078 0.158 _SSEPVKETVQTTQS(ph)PTPVEK_
SCAF8 Ubiquitylation K197 0.357 _VLNLWQK(gl)NNVFK_
SCAF8 Ubiquitylation K620 3.030 _IGSK(gl)VIK_
SCAF8 Phosphorylation T697 -0.087 _SSEPVKETVQTTQSPT(ph)PVEK_

Background Information for SCAF8:


Pubmed-SCAF8 »
Uniprot-SCAF8 »
Biogrid-SCAF8 »
ProteomicsDB-SCAF8 »

Tumorportal-SCAF8 »
COSMIC-SCAF8 »
GenomeRNAi-SCAF8 »
Genecards-SCAF8


Protein-protein Interactions for SCAF8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait DNPEP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM188A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTUS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAGK Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SCAF8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members RNA_pol_II-bd IPR006903 2.39
Category members CID_dom IPR006569 1.43
Category members ENTH_VHS IPR008942 0.96


Protein complexes (CORUM database) featuring SCAF8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1183 CDC5L complex Database 2.07


Categories featuring SCAF8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0003676 nucleic acid binding Database 0.83


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