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Query: SAP18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SAP18 0 2.226 -0.040 0.100
SAP18 0 2.226 -0.040 0.100 0.734 0.370 -0.445

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SAP18 Ubiquitylation K88 0.323 0.511 _ELTSLVK(gl)EVYPEAR_
SAP18 Ubiquitylation K128 0.956 0.189 _K(gl)GTDDSMTLQSQK_

Background Information for SAP18:


Pubmed-SAP18 »
Uniprot-SAP18 »
Biogrid-SAP18 »
ProteomicsDB-SAP18 »

Tumorportal-SAP18 »
COSMIC-SAP18 »
GenomeRNAi-SAP18 »
Genecards-SAP18


Protein-protein Interactions for SAP18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC22 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2B Cat. description Hein, Mann, Cell 2015


Protein Domains in SAP18
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SAP18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1257 ALL-1 supercomplex Database 4.3
Category members Corum 739 SIN3-ING1b complex II Database 4.24
Category members Corum 691 SIN3-SAP25 complex Database 1.77
Category members Corum 743 SIN3-SAP25 complex Database 1.77
Category members Corum 5614 Emerin complex 32 Database 1.48
Category members Corum 283 Sin3 complex Database 1.47
Category members Corum 54 SIN3 complex Database 1.47
Category members Corum 732 SIN3 complex Database 1.47
Category members Corum 738 SIN3-ING1b complex I Database 1.47
Category members Corum 760 Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18-RNPS1-Acinus-L Database 0.57
Category members Corum 761 Apoptosis- and splicing-associated protein complex (ASAP-S), SAP18-RNPS1-Acinus-S Database 0.57


Categories featuring SAP18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0048025 negative regulation of mRNA splicing, via spliceosome Database 2.79
Category members Pathway Pathway_881 PID_TELOMERASE_PATHWAY 0 2.64
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0061574 ASAP complex Database 0.57
Category members GO Category GO:0000381 regulation of alternative mRNA splicing, via spliceosome Database 0.5
Category members Pathway Pathway_845 PID_SMAD2_3NUCLEAR_PATHWAY 0 0.46
Category members GO Category GO:0035145 exon-exon junction complex Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members Pathway Pathway_984 PID_HEDGEHOG_GLI_PATHWAY 0 0.1
Category members GO Category GO:0000118 histone deacetylase complex Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0


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