bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SAFB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SAFB 1 4.368 -0.100 0.300 0.199 -0.309 0.131 0.259 0.318

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SAFB Phosphorylation S383 0.605 0.950 _ESSTSEGADQKMS(ph)SPEDDSDTKR_
SAFB Phosphorylation S384 0.426 0.610 _MSS(ph)PEDDSDTKR_
SAFB Phosphorylation S604 0.694 0.453 _SVVS(ph)FDKVK_
SAFB Phosphorylation S24 0.218 0.409 _(ac)AETLSGLGDSGAAGAAALSSASS(ph)ETGTR_
SAFB Phosphorylation S20 0.318 _(ac)AETLSGLGDSGAAGAAALS(ph)SASSETGTRR_
SAFB Phosphorylation S373 -0.044 _ESS(ph)TSEGADQKMSSPEDDSDTKR_
SAFB Phosphorylation S234 -0.054 -0.054 _SEPVKEES(ph)SELEQPFAQDTSSVGPDRK_
SAFB Phosphorylation S235 0.155 -0.209 _SEPVKEESS(ph)ELEQPFAQDTSSVGPDR_
SAFB Phosphorylation S227 -0.615 -0.426 _S(ph)EPVKEESSELEQPFAQDTSSVGPDR_
SAFB Phosphorylation S344 -1.775 -0.465 _TDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPS(ph)PEAR_
SAFB Phosphorylation S247 -0.662 -0.622 _SEPVKEESSELEQPFAQDTSS(ph)VGPDRK_
SAFB Phosphorylation T188 -0.570 -1.020 _ET(ph)INNLDTSSSDFTILQEIEEPSLEPENEK_
SAFB Ubiquitylation K392 -0.460 _MSSPEDDSDTK(gl)R_
SAFB Ubiquitylation K423 0.847 _ATDLK(gl)NLFSK_
SAFB Ubiquitylation K428 0.779 _NLFSK(gl)YGK_
SAFB Ubiquitylation K436 1.517 _VVGAK(gl)VVTNAR_
SAFB Ubiquitylation K475 1.241 _TELHGK(gl)MISVEK_

Background Information for SAFB:


Pubmed-SAFB »
Uniprot-SAFB »
Biogrid-SAFB »
ProteomicsDB-SAFB »

Tumorportal-SAFB »
COSMIC-SAFB »
GenomeRNAi-SAFB »
Genecards-SAFB


Protein-protein Interactions for SAFB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1CB Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait TBCK Cat. description Hein, Mann, Cell 2015
Category members IP bait APOBEC3D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAPN13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SAFB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members SAP_dom IPR003034 1.96


Protein complexes (CORUM database) featuring SAFB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SAFB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006325 chromatin organization Database 5.02
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003690 double-stranded DNA binding Database 0.66
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0001047 core promoter binding Database 0.11
Category members GO Category GO:0030520 intracellular estrogen receptor signaling pathway Database 0.06
Category members GO Category GO:0040007 growth Database 0
Category members GO Category GO:0042445 hormone metabolic process Database 0


.

© Copyright Svejstrup Laboratory 2015