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bioLOGIC Data

Query: RUFY1

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
RUFY1	0	0.220	-0.690	0.630

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
RUFY1	Ubiquitylation	K201		-1.479	_NLPELK(gl)TAVGR_
RUFY1	Ubiquitylation	K587	1.069		_MELQQVEGLKK(gl)_

Background Information for RUFY1:

Pubmed-RUFY1 »

Uniprot-RUFY1 »

Biogrid-RUFY1 »

ProteomicsDB-RUFY1 »

Tumorportal-RUFY1 »

COSMIC-RUFY1 »

GenomeRNAi-RUFY1 »

Genecards-RUFY1

Protein-protein Interactions for RUFY1

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait RUFY1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait ASPA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait C13orf18	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CD70	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CD79B	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FAS	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FOSL2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HSPBP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KIAA1984	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PMF1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RALBP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RUFY2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SNX8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ST8SIA1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ST8SIA4	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SYNC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TGOLN2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TIMM23	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait VSIG1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait WDFY2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in RUFY1

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Znf_FYVE_PHD	IPR011011	1.23
Category members	Znf_FYVE	IPR000306	0
Category members	Znf_RING	IPR001841	0
Category members	Run	IPR004012	0
Category members	Prefoldin	IPR009053	0
Category members	Znf_FYVE-rel	IPR017455	0

Protein complexes (CORUM database) featuring RUFY1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring RUFY1

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0015031	protein transport	Database	3.48
Category members	Pathway	Pathway_666	KEGG_ENDOCYTOSIS	0	1.25
Category members	GO Category	GO:0031901	early endosome membrane	Database	0.58
Category members	GO Category	GO:0006897	endocytosis	Database	0.31
Category members	GO Category	GO:0008270	zinc ion binding	Database	0.29
Category members	GO Category	GO:0008565	protein transporter activity	Database	0.26
Category members	GO Category	GO:0008289	lipid binding	Database	0
Category members	GO Category	GO:0030100	regulation of endocytosis	Database	0
Category members	GO Category	GO:0046872	metal ion binding	Database	0