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Query: RNF40

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNF40 0 1.456 0.590 -0.260 0.621 0.214 0.634 -0.322 -0.150

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNF40 Ubiquitylation K189 -0.308 _MEFSK(gl)AAVSR_
RNF40 Ubiquitylation K860 -0.901 _SQALELNK(gl)R_
RNF40 Ubiquitylation K420 0.767 _GLLLATK(gl)NSHLR_

Background Information for RNF40:





Protein-protein Interactions for RNF40

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait DTL Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF2H5 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait IWS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SARS Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2S Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB48 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC53 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DSN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM196A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRPLL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1F6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NELL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OIP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNAP29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCP10L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX13A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WAC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF232 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RNF40

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring RNF40

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1165 RNF20-RNF40-UbE2E1 complex Database 0.21


Categories featuring RNF40

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0010390 histone monoubiquitination Database 1.39
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0033523 histone H2B ubiquitination Database 0.77
Category members GO Category GO:0033503 HULC complex Database 0.54
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0017075 syntaxin-1 binding Database 0.09
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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