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Query: RNF213

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNF213 0 2.406 -0.030 0.150 0.735 0.428

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNF213 Ubiquitylation K1079 0.908 0.208 _ILANVTEDAK(gl)R_
RNF213 Phosphorylation S2273 0.353 -0.375 _DFATPSLHTSDQS(ph)PGK_
RNF213 Phosphorylation S1258 -0.455 -0.497 _EDQEAAELLS(ph)EPEEESER_
RNF213 Ubiquitylation K2016 -0.750 _MQLNVK(gl)NVPLK_
RNF213 Ubiquitylation K4312 -0.939 _DVVK(gl)QQGLR_

Background Information for RNF213:


Pubmed-RNF213 »
Uniprot-RNF213 »
Biogrid-RNF213 »
ProteomicsDB-RNF213 »

Tumorportal-RNF213 »
COSMIC-RNF213 »
GenomeRNAi-RNF213 »
Genecards-RNF213


Protein-protein Interactions for RNF213
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF4A Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL50 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTPN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2B Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2K Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD244 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCN2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RNF213
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring RNF213
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNF213
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0051865 protein autoubiquitination Database 0.18
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members Disease phenotype Moyamoya_disease Moyamoya disease Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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