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Query: RIOK2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RIOK2 0 2.373 -0.360 0.950

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RIOK2 Phosphorylation S27 0.780 0.643 _EGSEFS(ph)FSDGEVAEK_
RIOK2 Phosphorylation S29 0.578 0.519 _EGSEFSFS(ph)DGEVAEK_
RIOK2 Phosphorylation S74 0.493 _SSGDPEQIKEDSLS(ph)EESADAR_
RIOK2 Phosphorylation S72 -0.068 0.475 _SSGDPEQIKEDS(ph)LSEESADAR_
RIOK2 Phosphorylation S24 0.576 0.471 _EGS(ph)EFS(ph)FSDGEVAEK_
RIOK2 Phosphorylation S82 0.224 0.220 _S(ph)FEM(ox)TEFNQALEEIK_
RIOK2 Phosphorylation S134 -0.132 0.061 _VQGGVPAGS(ph)DEYEDECPHLIALSSLNR_

Background Information for RIOK2:


Pubmed-RIOK2 »
Uniprot-RIOK2 »
Biogrid-RIOK2 »
ProteomicsDB-RIOK2 »

Tumorportal-RIOK2 »
COSMIC-RIOK2 »
GenomeRNAi-RIOK2 »
Genecards-RIOK2


Protein-protein Interactions for RIOK2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP120 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS16 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RIOK2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members RIO_kinase IPR000687 0
Category members LipoPS_kinase IPR010440 0
Category members RIO-like_kinase IPR018934 0


Protein complexes (CORUM database) featuring RIOK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RIOK2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0009103 lipopolysaccharide biosynthetic process Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0016773 phosphotransferase activity, alcohol group as acceptor Database 0


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