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Query: RHOT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RHOT1 1 5.837 -1.960 3.470 0.712 0.810

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RHOT1 Ubiquitylation K187 0.526 0.319 _EMKPACIK(gl)ALTR_
RHOT1 Ubiquitylation K107 -0.322 _TDK(gl)DSRLPLILVGNK_

Background Information for RHOT1:


Pubmed-RHOT1 »
Uniprot-RHOT1 »
Biogrid-RHOT1 »
ProteomicsDB-RHOT1 »

Tumorportal-RHOT1 »
COSMIC-RHOT1 »
GenomeRNAi-RHOT1 »
Genecards-RHOT1


Protein-protein Interactions for RHOT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PEX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RHOT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RHOT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members EF_hand_assoc_1 IPR013566 0.29
Category members EF_hand_assoc_2 IPR013567 0.29
Category members Rho_GTPase_Mt IPR021181 0.29
Category members SRP_receptor_beta_su IPR019009 0.13
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring RHOT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RHOT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005741 mitochondrial outer membrane Database 0.46
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0031307 integral to mitochondrial outer membrane Database 0.24
Category members GO Category GO:0047497 mitochondrion transport along microtubule Database 0.23
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0019725 cellular homeostasis Database 0


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