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Query: RARS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RARS 0 1.722 1.460 -0.970 -0.057 0.442 0.324 0.293 0.530

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RARS Ubiquitylation K557 0.576 _LANIDEEMLQK(gl)AAR_
RARS Ubiquitylation K393 -0.263 -0.569 _SDGGYTYDTSDLAAIK(gl)QR_
RARS Ubiquitylation K306 -0.732 _NPDITK(gl)AWK_
RARS Ubiquitylation K20 0.056 _LLQQEEEIK(gl)SLTAEIDR_

Background Information for RARS:


Pubmed-RARS »
Uniprot-RARS »
Biogrid-RARS »
ProteomicsDB-RARS »

Tumorportal-RARS »
COSMIC-RARS »
GenomeRNAi-RARS »
Genecards-RARS


Protein-protein Interactions for RARS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait PKN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SDCCAG8 Cat. description Hein, Mann, Cell 2015
Category members IP bait TFG Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD68 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD93 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RARS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDCBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RARS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Arg-tRNA-ligase IPR001278 0
Category members Arg-tRNA-synth_N IPR005148 0
Category members DALR_anticod-bd IPR008909 0
Category members tRNAsynth_1a_anticodon-bd IPR009080 0


Protein complexes (CORUM database) featuring RARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3040 Multisynthetase complex Database 1.78


Categories featuring RARS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_201 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION 0 3.57
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0004812 aminoacyl-tRNA ligase activity Database 0.41
Category members GO Category GO:0017101 aminoacyl-tRNA synthetase multienzyme complex Database 0.11
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0004814 arginine-tRNA ligase activity Database 0
Category members GO Category GO:0006420 arginyl-tRNA aminoacylation Database 0
Category members GO Category GO:0034618 arginine binding Database 0


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