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Query: RAPGEF5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAPGEF5 0 -1.310 0.540 -0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAPGEF5 Phosphorylation S84 -0.405 -0.905 _RIS(ph)NPYLEHTPSQIYGENSSCAGR_

Background Information for RAPGEF5:


Pubmed-RAPGEF5 »
Uniprot-RAPGEF5 »
Biogrid-RAPGEF5 »
ProteomicsDB-RAPGEF5 »

Tumorportal-RAPGEF5 »
COSMIC-RAPGEF5 »
GenomeRNAi-RAPGEF5 »
Genecards-RAPGEF5


Protein-protein Interactions for RAPGEF5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAPGEF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAPGEF5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members DEP_dom IPR000591 0.07
Category members Ras-like_Gua-exchang_fac_N IPR000651 0
Category members RASGEF_cat_dom IPR001895 0
Category members Ras_GEF_dom IPR023578 0


Protein complexes (CORUM database) featuring RAPGEF5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAPGEF5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0005088 Ras guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0017034 Rap guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0030742 GTP-dependent protein binding Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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