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Query: RANBP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RANBP2 1 5.139 -0.030 -0.010 1.079 -0.385 0.549 0.456

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RANBP2 Ubiquitylation K2061 0.441 0.872 _GLGNLK(gl)ILK_
RANBP2 Ubiquitylation K106 0.667 _IAELLCK(gl)NDVTDGR_
RANBP2 Ubiquitylation K1220 0.641 _GIGNVK(gl)ILR_
RANBP2 Phosphorylation Y2666 0.598 _NRPDY(ph)VSEEEEDDEDFETAVKK_
RANBP2 Phosphorylation T2293 0.717 0.584 _LNQSGTSVGT(ph)DEESDVTQEEER_
RANBP2 Phosphorylation S796 0.553 0.575 _SYKYS(ph)PK_
RANBP2 Phosphorylation S2668 0.584 0.573 _NRPDYVS(ph)EEEEDDEDFETAVK_
RANBP2 Phosphorylation S3207 0.368 0.527 _IESFGS(ph)PK_
RANBP2 Phosphorylation S1456 0.018 0.508 _SGSSFVHQAS(ph)FK_
RANBP2 Phosphorylation S1573 0.499 _CVACQNPDKPS(ph)PSTSVPAPASFK_
RANBP2 Phosphorylation S2805 -0.018 0.448 _SISS(ph)PSVSSETMDKPVDLSTR_
RANBP2 Phosphorylation S2454 0.335 0.393 _DSLIT(ph)PHVS(ph)R_
RANBP2 Ubiquitylation K2379 -0.664 0.332 _DQVLK(gl)LCANHR_
RANBP2 Ubiquitylation K2358 0.436 0.327 _GIGDIK(gl)ILQNYDNK_
RANBP2 Ubiquitylation K2396 -0.954 0.190 _ITPDMTLQNMK(gl)GTER_
RANBP2 Phosphorylation S2280 0.065 0.135 _SALSPSKS(ph)PAK_
RANBP2 Phosphorylation S2510 -0.171 0.107 _AVVS(ph)PPKFVFGSESVK_
RANBP2 Phosphorylation S1400 -0.440 0.082 _ELVGPPLAETVFT(ph)PKTS(ph)PENVQDR_
RANBP2 Phosphorylation S955 -0.786 0.030 _FESPATGILS(ph)PR_
RANBP2 Phosphorylation S2276 0.074 0.029 _SALS(ph)PSKSPAK_
RANBP2 Ubiquitylation K2935 -1.498 0.007 _SGEEDEEILFK(gl)ER_
RANBP2 Phosphorylation S788 0.362 -0.041 _YSLS(ph)PSK_
RANBP2 Phosphorylation S21 0.047 -0.107 _YIASVQGSTPS(ph)PR_
RANBP2 Ubiquitylation K2592 -0.298 _NSDIEQSSDSK(gl)VK_
RANBP2 Ubiquitylation K2594 -0.298 _NSDIEQSSDSK(gl)VK_
RANBP2 Phosphorylation T1396 -0.510 -0.398 _ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR_
RANBP2 Phosphorylation S2900 -0.395 -0.513 _VGEDEDGS(ph)DEEVVHNEDIHFEPIVSLPEVEVK_
RANBP2 Ubiquitylation K776 -0.046 -0.521 _NADSEIK(gl)HSTPSPTR_
RANBP2 Ubiquitylation K94 -0.527 _SVELNPTQK(gl)DLVLK_
RANBP2 Phosphorylation S2250 1.539 -0.701 _EDALDDSVSSSSVHASPLAS(ph)SPVRK_
RANBP2 Phosphorylation T2613 -0.775 -0.709 _NLFASFPTEESSINYTFKT(ph)PEK_
RANBP2 Ubiquitylation K1963 -0.768 _STSGEGFQFGK(gl)K_
RANBP2 Ubiquitylation K1964 -0.768 _STSGEGFQFGK(gl)K_
RANBP2 Phosphorylation S1160 -1.328 _NHETDGGS(ph)AHGDDDDDGPHFEPVVPLPDKIEVK_
RANBP2 Phosphorylation T1399 -0.665 _ELVGPPLAETVFT(ph)PKT(ph)SPENVQDR_
RANBP2 Phosphorylation S2251 -0.023 _EDALDDSVSSSSVHASPLASS(ph)PVRK_
RANBP2 Ubiquitylation K2650 0.439 _ALATK(gl)LK_
RANBP2 Phosphorylation S2804 0.874 _SIS(ph)SPSVSSETM(ox)DKPVDLSTR_

Background Information for RANBP2:


Pubmed-RANBP2 »
Uniprot-RANBP2 »
Biogrid-RANBP2 »
ProteomicsDB-RANBP2 »

Tumorportal-RANBP2 »
COSMIC-RANBP2 »
GenomeRNAi-RANBP2 »
Genecards-RANBP2


Protein-protein Interactions for RANBP2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPF Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP155 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP214 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEH1L Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait B2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUSAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM194A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAF3IP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2I Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RANBP2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ran_bind_dom IPR000156 2.46
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members Cyclophilin-type_PPIase_dom IPR002130 0.54
Category members Cyclophilin-like_dom IPR029000 0.54
Category members Znf_RanBP2 IPR001876 0.18


Protein complexes (CORUM database) featuring RANBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RANBP2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_371 REACTOME_INFLUENZA_LIFE_CYCLE 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members Pathway Pathway_1310 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS 0 7.24
Category members Pathway Pathway_1311 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY 0 7.24
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0005643 nuclear pore Database 6.58
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members Pathway Pathway_886 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT 0 5.93
Category members GO Category GO:0010827 regulation of glucose transport Database 5.83
Category members GO Category GO:0007077 mitotic nuclear envelope disassembly Database 5.8
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_120 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN 0 5.24
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members GO Category GO:0006457 protein folding Database 4.93
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members GO Category GO:0008645 hexose transport Database 4.15
Category members Pathway Pathway_98 REACTOME_GLUCOSE_TRANSPORT 0 3.58
Category members Pathway Pathway_689 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 0 3.51
Category members GO Category GO:0046907 intracellular transport Database 3.25
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0031965 nuclear membrane Database 2.59
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0015758 glucose transport Database 2.09
Category members GO Category GO:0006606 protein import into nucleus Database 1.81
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0044615 nuclear pore nuclear basket Database 1.35
Category members Pathway Pathway_1254 PID_RANBP2_PATHWAY 0 1.33
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0042405 nuclear inclusion body Database 0.82
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members Disease phenotype Acute_necrotizing_encephalopathy_of_childhood Acute necrotizing encephalopathy of childhood Database 0.29
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members Disease phenotype Inflammatory_myofibroblastic_tumor Inflammatory myofibroblastic tumor Database 0.23
Category members GO Category GO:0008536 Ran GTPase binding Database 0.21
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0016874 ligase activity Database 0
Category members GO Category GO:0033132 negative regulation of glucokinase activity Database 0


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