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Query: RAB18

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RAB18 0 0.984 1.900 -0.740 0.023 0.389

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RAB18 Ubiquitylation K58 0.158 0.172 _TISVDGNKAK(gl)_
RAB18 Ubiquitylation K138 0.233 -0.286 _NEGLK(gl)FAR_
RAB18 Ubiquitylation K183 -0.099 -0.335 _IIQTPGLWESENQNK(gl)GVK_
RAB18 Ubiquitylation K56 0.134 _TISVDGNK(gl)AK_
RAB18 Ubiquitylation K142 0.400 _K(gl)HSM(ox)LFIEASAK_

Background Information for RAB18:


Pubmed-RAB18 »
Uniprot-RAB18 »
Biogrid-RAB18 »
ProteomicsDB-RAB18 »

Tumorportal-RAB18 »
COSMIC-RAB18 »
GenomeRNAi-RAB18 »
Genecards-RAB18


Protein-protein Interactions for RAB18
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AGK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RAB18
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Ran_GTPase IPR002041 1.25
Category members Small_GTPase_ARF/SAR IPR006689 0.8
Category members Small_GTPase_Ras IPR020849 0.7
Category members Small_GTPase_Rho IPR003578 0.65
Category members Small_GTPase IPR001806 0.65
Category members Gtr1_RagA IPR006762 0.63
Category members Small_GTPase_Rab_type IPR003579 0.51
Category members MIRO-like IPR013684 0.4
Category members Small_GTP-bd_dom IPR005225 0.32
Category members Small_GTPase_ARF IPR024156 0


Protein complexes (CORUM database) featuring RAB18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RAB18
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006913 nucleocytoplasmic transport Database 2.96
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Disease phenotype Micro_syndrome Micro syndrome Database 0.11
Category members GO Category GO:0001654 eye development Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007420 brain development Database 0


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