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Query: PYGL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PYGL 1 4.490 0.220 -0.250
PYGL 1 4.490 0.220 -0.250 -2.175 -0.336
PYGL 1 4.490 0.220 -0.250 1.354 1.739

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PYGL Ubiquitylation K30 0.225 _GIVGVENVAELKK(gl)_
PYGL Ubiquitylation K804 1.172 0.214 _AWNTMVLK(gl)NIAASGK_
PYGL Ubiquitylation K724 -0.011 0.111 _IDDVAALDK(gl)K_
PYGL Ubiquitylation K460 0.084 _MSVIEEGDCK(gl)R_
PYGL Ubiquitylation K170 -0.689 -0.151 _YEYGIFNQK(gl)IR_
PYGL Ubiquitylation K32 -0.285 _(ac)AKPLTDSEK(gl)R_
PYGL Ubiquitylation K811 -0.458 _NIAASGK(gl)FSSDR_
PYGL Ubiquitylation K467 -0.475 _IHSDIVKTK(gl)_
PYGL Ubiquitylation K438 -0.631 _MSLIEEEGSK(gl)R_
PYGL Ubiquitylation K569 -0.715 _INPSSMFDVQVK(gl)R_
PYGL Ubiquitylation K10 -1.798 -0.985 _(ac)AKPLTDQEK(gl)R_
PYGL Ubiquitylation K3 -1.000 _(ac)AK(gl)PLTDQEK_
PYGL Ubiquitylation K290 -1.900 _VLYPNDNFFEGK(gl)ELR_
PYGL Ubiquitylation K421 -1.738 _IVALFPK(gl)DVDR_
PYGL Ubiquitylation K725 -0.011 _IDDVAALDK(gl)K_

Background Information for PYGL:


Pubmed-PYGL »
Uniprot-PYGL »
Biogrid-PYGL »
ProteomicsDB-PYGL »

Tumorportal-PYGL »
COSMIC-PYGL »
GenomeRNAi-PYGL »
Genecards-PYGL


Protein-protein Interactions for PYGL
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DCAF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NTF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFP41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PYGL
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyco_trans_35 IPR000811 0
Category members Glycg_phsphrylas IPR011833 0


Protein complexes (CORUM database) featuring PYGL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PYGL
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_67 BIOCARTA_FEEDER_PATHWAY 0 0.39
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members Pathway Pathway_66 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS 0 0.22
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0005980 glycogen catabolic process Database 0.2
Category members GO Category GO:0016208 AMP binding Database 0.2
Category members GO Category GO:0042593 glucose homeostasis Database 0.18
Category members GO Category GO:0005977 glycogen metabolic process Database 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process Database 0.07
Category members Pathway Pathway_60 KEGG_STARCH_AND_SUCROSE_METABOLISM 0 0
Category members GO Category GO:0002060 purine nucleobase binding Database 0
Category members GO Category GO:0004645 phosphorylase activity Database 0
Category members GO Category GO:0005536 glucose binding Database 0
Category members GO Category GO:0008144 drug binding Database 0
Category members GO Category GO:0008184 glycogen phosphorylase activity Database 0
Category members GO Category GO:0019842 vitamin binding Database 0
Category members GO Category GO:0030170 pyridoxal phosphate binding Database 0
Category members GO Category GO:0030246 carbohydrate binding Database 0
Category members GO Category GO:0032052 bile acid binding Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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