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Query: PUM2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PUM2 2 3.801 0.730 -0.940

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PUM2 Phosphorylation S182 1.641 2.452 _QAS(ph)PTEVVER_
PUM2 Phosphorylation S82 0.718 0.923 _SGQGFHGNSEVNAILS(ph)PR_
PUM2 Ubiquitylation K596 -1.213 0.893 _ESLSTSSDLYK(gl)R_
PUM2 Phosphorylation S587 1.669 0.831 _RES(ph)LSTSSDLYK_
PUM2 Phosphorylation S136 0.233 0.306 _GKAS(ph)PFEEDQNR_

Background Information for PUM2:


Pubmed-PUM2 »
Uniprot-PUM2 »
Biogrid-PUM2 »
ProteomicsDB-PUM2 »

Tumorportal-PUM2 »
COSMIC-PUM2 »
GenomeRNAi-PUM2 »
Genecards-PUM2


Protein-protein Interactions for PUM2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RBM45 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CELF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLASRP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBFOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PUM2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members Pumilio_RNA-bd_rpt IPR001313 0


Protein complexes (CORUM database) featuring PUM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PUM2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0010494 cytoplasmic stress granule Database 1.32
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0034063 stress granule assembly Database 0.13
Category members GO Category GO:0006417 regulation of translation Database 0


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