bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PTTG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTTG1 1 -1.625 -1.960 3.490

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTTG1 Phosphorylation S165 -1.353 -0.939 _LFQLGPPS(ph)PVK_
PTTG1 Ubiquitylation K25 -1.469 -1.355 _DGLK(gl)LGSGPSIK_
PTTG1 Ubiquitylation K21 -1.438 _VVAK(gl)DGLK_
PTTG1 Ubiquitylation K48 -2.125 -2.226 _FGK(gl)TFDAPPALPK_

Background Information for PTTG1:


Pubmed-PTTG1 »
Uniprot-PTTG1 »
Biogrid-PTTG1 »
ProteomicsDB-PTTG1 »

Tumorportal-PTTG1 »
COSMIC-PTTG1 »
GenomeRNAi-PTTG1 »
Genecards-PTTG1


Protein-protein Interactions for PTTG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PTTG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PTTG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PTTG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Securin_separation_inhibitor IPR006940 0.31


Protein complexes (CORUM database) featuring PTTG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5642 Securin-separase complex Database 0.31


Categories featuring PTTG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members GO Category GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Database 2.59
Category members Pathway Pathway_780 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 0 2.46
Category members Pathway Pathway_784 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS 0 2.26
Category members GO Category GO:0007067 mitosis Database 2.23
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members Pathway Pathway_788 REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE 0 1.91
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0051276 chromosome organization Database 0.1
Category members GO Category GO:0004869 cysteine-type endopeptidase inhibitor activity Database 0
Category members GO Category GO:0006259 DNA metabolic process Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0


.

© Copyright Svejstrup Laboratory 2015