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Query: PTGES2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PTGES2 0 -1.646 1.440 -0.360
PTGES2 0 -1.646 1.440 -0.360 0.198 -0.717 -0.743

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PTGES2 Ubiquitylation K141 -0.517 0.132 _RAEIK(gl)FSSYR_

Background Information for PTGES2:


Pubmed-PTGES2 »
Uniprot-PTGES2 »
Biogrid-PTGES2 »
ProteomicsDB-PTGES2 »

Tumorportal-PTGES2 »
COSMIC-PTGES2 »
GenomeRNAi-PTGES2 »
Genecards-PTGES2


Protein-protein Interactions for PTGES2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABCF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP6V0D1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C5orf28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DLK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EID3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FUZ Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RANBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB2A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SHISA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRQ Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PTGES2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Thioredoxin-like_fold IPR012336 0.16
Category members Glutaredoxin IPR002109 0.06
Category members GST_C IPR004046 0


Protein complexes (CORUM database) featuring PTGES2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PTGES2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0043295 glutathione binding Database 0.53
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members Pathway Pathway_158 KEGG_ARACHIDONIC_ACID_METABOLISM 0 0.13
Category members Pathway Pathway_537 PID_IFNG_PATHWAY 0 0.11
Category members GO Category GO:0001516 prostaglandin biosynthetic process Database 0.09
Category members GO Category GO:0045454 cell redox homeostasis Database 0.05
Category members GO Category GO:0020037 heme binding Database 0.04
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0015035 protein disulfide oxidoreductase activity Database 0
Category members GO Category GO:0016829 lyase activity Database 0
Category members GO Category GO:0046903 secretion Database 0
Category members GO Category GO:0050220 prostaglandin-E synthase activity Database 0


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