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Query: PSIP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PSIP1 1 6.105 0.070 -0.030 -0.260 0.186 0.823

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PSIP1 Ubiquitylation K364 0.601 1.008 _NSLK(gl)IDNLDVNR_
PSIP1 Phosphorylation S273 0.519 0.996 _TGVTSTS(ph)DSEEEGDDQEGEK_
PSIP1 Phosphorylation T122 1.342 0.978 _EDT(ph)DHEEKASNEDVTK_
PSIP1 Phosphorylation S129 0.838 0.918 _ETSVSKEDTDHEEKAS(ph)NEDVTK_
PSIP1 Phosphorylation S275 0.876 0.849 _TGVTSTSDS(ph)EEEGDDQEGEK_
PSIP1 Phosphorylation S106 0.778 0.738 _QSNASS(ph)DVEVEEK_
PSIP1 Phosphorylation S105 0.843 0.575 _QSNAS(ph)SDVEVEEKETSVSKEDTDHEEK_
PSIP1 Ubiquitylation K65 0.538 0.265 _DIFPYSENK(gl)EK_
PSIP1 Ubiquitylation K67 0.265 _DIFPYSENK(gl)EK_
PSIP1 Phosphorylation T141 -0.754 0.009 _AVDITT(ph)PK_
PSIP1 Phosphorylation T272 -0.086 _TGVTST(ph)SDSEEEGDDQEGEK_
PSIP1 Phosphorylation S522 -0.176 -0.100 _ETEIS(ph)LKDSTLDN_
PSIP1 Ubiquitylation K6 2.009 _DFK(gl)PGDLIFAK_
PSIP1 Ubiquitylation K91 1.359 _VK(gl)FSSQQAATK_
PSIP1 Ubiquitylation K135 1.360 _ASNEDVTK(gl)AVDITTPK_
PSIP1 Ubiquitylation K143 1.222 _AVDITTPK(gl)AAR_
PSIP1 Ubiquitylation K360 0.465 _IHAEIK(gl)NSLK_
PSIP1 Ubiquitylation K401 0.922 _HTEMITTLK(gl)K_
PSIP1 Ubiquitylation K424 0.779 _STMLYNKFK(gl)_

Background Information for PSIP1:


Pubmed-PSIP1 »
Uniprot-PSIP1 »
Biogrid-PSIP1 »
ProteomicsDB-PSIP1 »

Tumorportal-PSIP1 »
COSMIC-PSIP1 »
GenomeRNAi-PSIP1 »
Genecards-PSIP1


Protein-protein Interactions for PSIP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3A Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3E Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VIM Cat. description Hein, Mann, Cell 2015


Protein Domains in PSIP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PWWP_dom IPR000313 0.63
Category members Treacle-like_TCS IPR017859 0.35


Protein complexes (CORUM database) featuring PSIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PSIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members Pathway Pathway_196 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 0 9.67
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_1206 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS 0 6.87
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005720 nuclear heterochromatin Database 1.41
Category members GO Category GO:0034399 nuclear periphery Database 1.34
Category members Pathway Pathway_859 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE 0 1.34
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_981 REACTOME_INTEGRATION_OF_PROVIRUS 0 0.76
Category members GO Category GO:0000395 mRNA 5'-splice site recognition Database 0.43
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0035327 transcriptionally active chromatin Database 0.04
Category members Pathway Pathway_1313 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION 0 0
Category members GO Category GO:0001105 RNA polymerase II transcription coactivator activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0009408 response to heat Database 0
Category members GO Category GO:0033613 activating transcription factor binding Database 0


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