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Query: PRPSAP2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRPSAP2 0 -3.236 -0.140 0.350
PRPSAP2 0 -3.236 -0.140 0.350 0.742 -1.568 -1.133 -0.179

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRPSAP2 Phosphorylation S219 0.469 0.279 _LGIAVIHGEAQDAES(ph)DLVDGRHSPPMVR_
PRPSAP2 Phosphorylation S227 -0.035 0.105 _LGIAVIHGEAQDAESDLVDGRHS(ph)PPMVR_
PRPSAP2 Phosphorylation T5 -0.038 -0.002 _(ac)M(ox)FCVT(ph)PPELETK_
PRPSAP2 Ubiquitylation K188 -0.767 _NAVIVAK(gl)SPASAK_
PRPSAP2 Ubiquitylation K238 -1.430 -1.796 _EK(gl)PPITVVGDVGGR_

Background Information for PRPSAP2:





Protein-protein Interactions for PRPSAP2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPSAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPSAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRPSAP2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PRTase-like IPR029057 0.32
Category members Rib-P_diPkinase IPR005946 0.2


Protein complexes (CORUM database) featuring PRPSAP2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRPSAP2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0002189 ribose phosphate diphosphokinase complex Database 0.48
Category members GO Category GO:0004749 ribose phosphate diphosphokinase activity Database 0.2
Category members GO Category GO:0009165 nucleotide biosynthetic process Database 0.17
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0004857 enzyme inhibitor activity Database 0
Category members GO Category GO:0043086 negative regulation of catalytic activity Database 0
Category members GO Category GO:0060348 bone development Database 0


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