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Query: PRPSAP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRPSAP1 0 0.484 -0.670 0.660

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRPSAP1 Ubiquitylation K24 -0.285 -0.046 _VFSANSTAACTELAK(gl)R_
PRPSAP1 Phosphorylation S215 0.241 -0.086 _LGLAVIHGEAQCTELDM(ox)DDGRHS(ph)PPM(ox)VK_
PRPSAP1 Ubiquitylation K176 -0.467 -1.017 _NAVIVAK(gl)SPDAAKR_
PRPSAP1 Ubiquitylation K238 -1.430 -1.796 _EK(gl)PPITVVGDVGGR_
PRPSAP1 Ubiquitylation K52 -0.423 _VEIK(gl)ESVR_

Background Information for PRPSAP1:


Pubmed-PRPSAP1 »
Uniprot-PRPSAP1 »
Biogrid-PRPSAP1 »
ProteomicsDB-PRPSAP1 »

Tumorportal-PRPSAP1 »
COSMIC-PRPSAP1 »
GenomeRNAi-PRPSAP1 »
Genecards-PRPSAP1


Protein-protein Interactions for PRPSAP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAPGEF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMG9 Cat. description Hein, Mann, Cell 2015
Category members IP bait WIZ Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf71 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPSAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRPSAP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PRTase-like IPR029057 0.32
Category members Rib-P_diPkinase IPR005946 0.2


Protein complexes (CORUM database) featuring PRPSAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRPSAP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0002189 ribose phosphate diphosphokinase complex Database 0.48
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0004749 ribose phosphate diphosphokinase activity Database 0.2
Category members GO Category GO:0009165 nucleotide biosynthetic process Database 0.17
Category members GO Category GO:0006139 nucleobase-containing compound metabolic process Database 0.08
Category members GO Category GO:0033673 negative regulation of kinase activity Database 0.07
Category members GO Category GO:0030234 enzyme regulator activity Database 0.02
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0004857 enzyme inhibitor activity Database 0


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