bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: PRPF4B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRPF4B 0 4.998 -0.470 -0.010
PRPF4B 0 4.998 -0.470 -0.010 0.994 0.726 0.488 0.136 0.264

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRPF4B Phosphorylation S280 1.312 1.402 _SRS(ph)PVDLR_
PRPF4B Phosphorylation S243 0.893 0.869 _ARS(ph)PTDDKVK_
PRPF4B Phosphorylation S263 0.681 0.659 _KS(ph)PIINESR_
PRPF4B Phosphorylation S417 0.565 _DAS(ph)PINRWS(ph)PTR_
PRPF4B Phosphorylation S423 0.565 _DAS(ph)PINRWS(ph)PTR_
PRPF4B Phosphorylation Y835 0.441 0.449 _LCDFGSASHVADNDITPY(ph)LVSR_
PRPF4B Phosphorylation S838 -0.194 0.423 _LCDFGSASHVADNDITPYLVS(ph)R_
PRPF4B Phosphorylation T245 0.305 0.249 _ARS(ph)PTDDKVK_
PRPF4B Ubiquitylation K656 -0.314 _AAGIGK(gl)DFKENPNLR_

Background Information for PRPF4B:


Pubmed-PRPF4B »
Uniprot-PRPF4B »
Biogrid-PRPF4B »
ProteomicsDB-PRPF4B »

Tumorportal-PRPF4B »
COSMIC-PRPF4B »
GenomeRNAi-PRPF4B »
Genecards-PRPF4B


Protein-protein Interactions for PRPF4B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AKAP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSP90AA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF1C Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCD Cat. description Hein, Mann, Cell 2015
Category members IP bait SART3 Cat. description Hein, Mann, Cell 2015
Category members IP bait XPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRPF4B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring PRPF4B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring PRPF4B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


.

© Copyright Svejstrup Laboratory 2015