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Query: PRPF40A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRPF40A 0 3.469 0.270 -0.400 1.069 0.440 0.924 -0.231 0.314

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRPF40A Phosphorylation S938 -0.360 0.363 _DSGNWDTSGSELS(ph)EGELEKR_
PRPF40A Phosphorylation S888 0.125 0.348 _SDSPES(ph)DAEREK_
PRPF40A Ubiquitylation K150 0.396 _SMWTEHK(gl)SPDGR_
PRPF40A Ubiquitylation K196 0.465 _SDSGK(gl)PYYYNSQTK_

Background Information for PRPF40A:


Pubmed-PRPF40A »
Uniprot-PRPF40A »
Biogrid-PRPF40A »
ProteomicsDB-PRPF40A »

Tumorportal-PRPF40A »
COSMIC-PRPF40A »
GenomeRNAi-PRPF40A »
Genecards-PRPF40A


Protein-protein Interactions for PRPF40A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTR1B Cat. description Hein, Mann, Cell 2015
Category members IP bait AMOT Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GNPNAT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUP Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEDD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEIL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NR2C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait OSGEP Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1R35 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRSS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS16 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf80 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF40A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC30A4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPATA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRPF40A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FF_domain IPR002713 1.23
Category members WW_dom IPR001202 1.15
Category members Antifreeze_1 IPR000104 0.24


Protein complexes (CORUM database) featuring PRPF40A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3


Categories featuring PRPF40A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0032465 regulation of cytokinesis Database 0.05
Category members GO Category GO:0070064 proline-rich region binding Database 0.01
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0016477 cell migration Database 0


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