bioLOGIC-db

bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

Query: PRKRA

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
W

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
PRKRA	0	4.642	-1.380	2.380				0.767	0.127

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
PRKRA	Phosphorylation	T20	0.658	0.710	_EDSGT(ph)FSLGK_
PRKRA	Phosphorylation	S18	0.646	0.502	_EDS(ph)GTFSLGK_

Background Information for PRKRA:

Pubmed-PRKRA »

Uniprot-PRKRA »

Biogrid-PRKRA »

ProteomicsDB-PRKRA »

Tumorportal-PRKRA »

COSMIC-PRKRA »

GenomeRNAi-PRKRA »

Genecards-PRKRA

Protein-protein Interactions for PRKRA

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait WDR5	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait DGCR8	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ELAVL2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ILF2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MAGEB10	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RALYL	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RASL10A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RBM34	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RPL18A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RPL30	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait STAU1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait STRBP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait WDR46	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in PRKRA

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	dsRNA-bd_dom	IPR014720	0.23

Protein complexes (CORUM database) featuring PRKRA

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring PRKRA

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0003723	RNA binding	Database	INF
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0010467	gene expression	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	GO Category	GO:0006955	immune response	Database	1.22
Category members	GO Category	GO:0043085	positive regulation of catalytic activity	Database	0.78
Category members	GO Category	GO:0048471	perinuclear region of cytoplasm	Database	0.39
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0008285	negative regulation of cell proliferation	Database	0.28
Category members	GO Category	GO:0016301	kinase activity	Database	0.23
Category members	GO Category	GO:0008047	enzyme activator activity	Database	0.15
Category members	GO Category	GO:0006468	protein phosphorylation	Database	0.04
Category members	Pathway	Pathway_734	PID_CERAMIDE_PATHWAY	0	0
Category members	GO Category	GO:0006950	response to stress	Database	0
Category members	GO Category	GO:0009615	response to virus	Database	0
Category members	GO Category	GO:0030422	production of siRNA involved in RNA interference	Database	0
Category members	GO Category	GO:0034599	cellular response to oxidative stress	Database	0
Category members	GO Category	GO:0042473	outer ear morphogenesis	Database	0
Category members	GO Category	GO:0042474	middle ear morphogenesis	Database	0
Category members	GO Category	GO:0042803	protein homodimerization activity	Database	0
Category members	GO Category	GO:0048705	skeletal system morphogenesis	Database	0