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Query: PRDX3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRDX3 0 3.101 -0.130 1.040 0.740 0.459 -0.867 1.026 0.703

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PRDX3:


Pubmed-PRDX3 »
Uniprot-PRDX3 »
Biogrid-PRDX3 »
ProteomicsDB-PRDX3 »

Tumorportal-PRDX3 »
COSMIC-PRDX3 »
GenomeRNAi-PRDX3 »
Genecards-PRDX3


Protein-protein Interactions for PRDX3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDC42 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C4 Cat. description Hein, Mann, Cell 2015
Category members IP bait MARK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MSN Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6A Cat. description Hein, Mann, Cell 2015
Category members IP bait PCNA Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMD6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait SPRED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRDX3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRDX3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peroxiredoxin_C IPR019479 1.06
Category members Redoxin IPR013740 0.19
Category members Thioredoxin-like_fold IPR012336 0.16
Category members AhpC/TSA IPR000866 0.13


Protein complexes (CORUM database) featuring PRDX3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRDX3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051881 regulation of mitochondrial membrane potential Database 1.57
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0005769 early endosome Database 1.26
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0051920 peroxiredoxin activity Database 0.94
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0019900 kinase binding Database 0.45
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0042542 response to hydrogen peroxide Database 0.19
Category members GO Category GO:0008385 IkappaB kinase complex Database 0.13
Category members GO Category GO:0033673 negative regulation of kinase activity Database 0.07
Category members GO Category GO:0016209 antioxidant activity Database 0.06
Category members GO Category GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process Database 0.05
Category members GO Category GO:0001893 maternal placenta development Database 0
Category members GO Category GO:0004601 peroxidase activity Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0007005 mitochondrion organization Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0030099 myeloid cell differentiation Database 0
Category members GO Category GO:0034614 cellular response to reactive oxygen species Database 0
Category members GO Category GO:0042744 hydrogen peroxide catabolic process Database 0
Category members GO Category GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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