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Query: PRDX2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRDX2 0 1.897 0.830 -0.090 0.376 -0.202 0.113 0.594

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRDX2 Ubiquitylation K29 -1.244 0.469 _ATAVVDGAFKEVK(gl)_
PRDX2 Ubiquitylation K10 -0.538 -0.305 _IGK(gl)PAPDFK_
PRDX2 Ubiquitylation K119 0.547 _LSEDYGVLK(gl)TDEGIAYR_

Background Information for PRDX2:


Pubmed-PRDX2 »
Uniprot-PRDX2 »
Biogrid-PRDX2 »
ProteomicsDB-PRDX2 »

Tumorportal-PRDX2 »
COSMIC-PRDX2 »
GenomeRNAi-PRDX2 »
Genecards-PRDX2


Protein-protein Interactions for PRDX2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC15 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM134A Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait PRDX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNASEH2A Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait TOR1AIP1 Cat. description Hein, Mann, Cell 2015


Protein Domains in PRDX2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Peroxiredoxin_C IPR019479 1.06
Category members Redoxin IPR013740 0.19
Category members Thioredoxin-like_fold IPR012336 0.16
Category members AhpC/TSA IPR000866 0.13


Protein complexes (CORUM database) featuring PRDX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRDX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0051920 peroxiredoxin activity Database 0.94
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0008379 thioredoxin peroxidase activity Database 0.35
Category members GO Category GO:0016209 antioxidant activity Database 0.06
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0019430 removal of superoxide radicals Database 0
Category members GO Category GO:0034599 cellular response to oxidative stress Database 0
Category members GO Category GO:0042744 hydrogen peroxide catabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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