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Query: PRCC

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRCC 0 -3.327 1.180 -0.390
PRCC 0 -3.327 1.180 -0.390 -2.401 -2.302

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRCC Phosphorylation S159 -0.308 0.452 _IAAPELHKGDSDS(ph)EEDEPTK_
PRCC Phosphorylation S157 -1.061 0.252 _IAAPELHKGDS(ph)DSEEDEPTK_
PRCC Phosphorylation S209 0.555 -0.234 _KPS(ph)DGSPDTKPSR_
PRCC Phosphorylation T237 -0.539 _TSSLAPVVGTTT(ph)TTPSPSAIK_
PRCC Phosphorylation S212 -0.631 -0.637 _KPSDGS(ph)PDTKPSR_
PRCC Phosphorylation S241 -0.552 -1.061 _TSSLAPVVGTTTTTPS(ph)PSAIK_
PRCC Ubiquitylation K479 0.119 _NTWSENK(gl)LSR_
PRCC Ubiquitylation K488 0.369 _RQTQAK(gl)YGF_

Background Information for PRCC:


Pubmed-PRCC »
Uniprot-PRCC »
Biogrid-PRCC »
ProteomicsDB-PRCC »

Tumorportal-PRCC »
COSMIC-PRCC »
GenomeRNAi-PRCC »
Genecards-PRCC


Protein-protein Interactions for PRCC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCAS2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CRNKL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait IWS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRP8 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PIM2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YWHAZ Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF281 Cat. description Hein, Mann, Cell 2015
Category members IP bait FKBP9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WRAP73 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRCC
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PRCC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRCC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0007093 mitotic cell cycle checkpoint Database 0.27
Category members Disease phenotype Translocation_renal_cell_carcinoma Translocation renal cell carcinoma Database 0


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