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Query: PPP6R1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP6R1 0 -6.918 0.090 -0.500 -0.409 -0.832 -0.048 -1.875

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP6R1 Ubiquitylation K190 -0.812 _QDVVNWLNEEK(gl)IVQR_
PPP6R1 Phosphorylation S759 -1.430 -1.512 _VSGEEELHTGPPAPQGPLSVPQGLPTQSLAS(ph)PPAR_
PPP6R1 Ubiquitylation K480 -1.674 _VAGALVQNTEK(gl)GPNAEQLR_

Background Information for PPP6R1:


Pubmed-PPP6R1 »
Uniprot-PPP6R1 »
Biogrid-PPP6R1 »
ProteomicsDB-PPP6R1 »

Tumorportal-PPP6R1 »
COSMIC-PPP6R1 »
GenomeRNAi-PPP6R1 »
Genecards-PPP6R1


Protein-protein Interactions for PPP6R1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANKRD28 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6C Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANKRD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCLRE1C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNKD Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP6R1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members SAPS IPR007587 0.6


Protein complexes (CORUM database) featuring PPP6R1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5196 TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1) Database 1.67


Categories featuring PPP6R1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019903 protein phosphatase binding Database 0.33
Category members GO Category GO:0043666 regulation of phosphoprotein phosphatase activity Database 0


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