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Query: PPP2R4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPP2R4 0 -0.719 1.550 -0.940

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPP2R4 Ubiquitylation K138 -0.096 _FGNK(gl)AYR_
PPP2R4 Ubiquitylation K331 -0.624 _MYK(gl)AECLEK_

Background Information for PPP2R4:


Pubmed-PPP2R4 »
Uniprot-PPP2R4 »
Biogrid-PPP2R4 »
ProteomicsDB-PPP2R4 »

Tumorportal-PPP2R4 »
COSMIC-PPP2R4 »
GenomeRNAi-PPP2R4 »
Genecards-PPP2R4


Protein-protein Interactions for PPP2R4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP2R4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMEK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPP2R4
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PPP2R4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PPP2R4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006457 protein folding Database 4.93
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0006200 ATP catabolic process Database 2.13
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31
Category members Pathway Pathway_123 BIOCARTA_CHREBP2_PATHWAY 0 0.61
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0000413 protein peptidyl-prolyl isomerization Database 0.25
Category members GO Category GO:0034704 calcium channel complex Database 0.21
Category members Pathway Pathway_142 PID_MYC_REPRESS_PATHWAY 0 0.21
Category members GO Category GO:0000159 protein phosphatase type 2A complex Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0008160 protein tyrosine phosphatase activator activity Database 0
Category members GO Category GO:0008601 protein phosphatase type 2A regulator activity Database 0
Category members GO Category GO:0019211 phosphatase activator activity Database 0
Category members GO Category GO:0032515 negative regulation of phosphoprotein phosphatase activity Database 0
Category members GO Category GO:0032516 positive regulation of phosphoprotein phosphatase activity Database 0
Category members GO Category GO:0035307 positive regulation of protein dephosphorylation Database 0
Category members GO Category GO:0035308 negative regulation of protein dephosphorylation Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043666 regulation of phosphoprotein phosphatase activity Database 0
Category members GO Category GO:0051721 protein phosphatase 2A binding Database 0


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