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Query: PPIL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PPIL1 0 -3.335 0.760 0.070 -0.749 -2.249 -0.866

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PPIL1 Phosphorylation T147 0.597 _VGMVET(ph)NSQDRPVDDVK_
PPIL1 Phosphorylation S149 -0.076 0.410 _VGMVETNS(ph)QDRPVDDVK_
PPIL1 Ubiquitylation K80 -0.243 _GGASIYGK(gl)QFEDELHPDLK_
PPIL1 Ubiquitylation K161 0.008 _IIK(gl)AYPSG_

Background Information for PPIL1:





Protein-protein Interactions for PPIL1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SNW1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait PPIL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PPIL1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cyclophilin-type_PPIase_dom IPR002130 0.54
Category members Cyclophilin-like_dom IPR029000 0.54


Protein complexes (CORUM database) featuring PPIL1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring PPIL1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31


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