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Query: POFUT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
POFUT1 0 1.047 -0.040 0.310

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
POFUT1 Ubiquitylation K246 0.737 _IGSDWK(gl)NACAMLK_

Background Information for POFUT1:


Pubmed-POFUT1 »
Uniprot-POFUT1 »
Biogrid-POFUT1 »
ProteomicsDB-POFUT1 »

Tumorportal-POFUT1 »
COSMIC-POFUT1 »
GenomeRNAi-POFUT1 »
Genecards-POFUT1


Protein-protein Interactions for POFUT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXO6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in POFUT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GDP-Fuc_O-FucTrfase IPR019378 0


Protein complexes (CORUM database) featuring POFUT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring POFUT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016266 O-glycan processing Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members GO Category GO:0006493 protein O-linked glycosylation Database 0.32
Category members GO Category GO:0016757 transferase activity, transferring glycosyl groups Database 0.19
Category members Pathway Pathway_113 REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 0 0.08
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members Disease phenotype DOWLING-DEGOS_DISEASE DOWLING-DEGOS DISEASE Database 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0001756 somitogenesis Database 0
Category members GO Category GO:0006004 fucose metabolic process Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0008417 fucosyltransferase activity Database 0
Category members GO Category GO:0009790 embryo development Database 0
Category members GO Category GO:0036066 protein O-linked fucosylation Database 0
Category members GO Category GO:0046922 peptide-O-fucosyltransferase activity Database 0


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