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Query: PNN

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PNN 2 5.997 -1.000 1.720 0.697 0.186 0.165 -0.089 -0.064

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PNN Phosphorylation S381 1.691 1.654 _QQDS(ph)QPEEVM(ox)DVLEM(ox)VENVK_
PNN Phosphorylation S375 1.918 1.229 _ES(ph)EKQQDSQPEEVMDVLEM(ox)VENVK_
PNN Phosphorylation S347 0.676 0.756 _EIAIVHS(ph)DAEKEQEEEEQKQEM(ox)EVK_
PNN Phosphorylation S443 0.564 0.502 _SLS(ph)PGKENVSALDMEK_
PNN Phosphorylation S441 0.535 0.333 _S(ph)LSPGKENVSALDMEK_
PNN Phosphorylation S100 -0.228 0.216 _QES(ph)DPEDDDVKKPALQSSVVATSK_
PNN Phosphorylation S66 1.278 0.098 _GFS(ph)DSGGGPPAK_
PNN Ubiquitylation K137 -0.413 _DLIQDQNMDEK(gl)GK_
PNN Ubiquitylation K139 -0.190 _DLIQDQNMDEKGK(gl)_

Background Information for PNN:





Protein-protein Interactions for PNN

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM8A Cat. description Hein, Mann, Cell 2015
Category members IP bait SPRED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait WASH3P Cat. description Hein, Mann, Cell 2015
Category members IP bait AKAP17A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf80 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGOH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF40A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALYL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SARNP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SREK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait U2AF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCCHC17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PNN

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PNN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1181 C complex spliceosome Database 2.39


Categories featuring PNN

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0035145 exon-exon junction complex Database 0.28
Category members GO Category GO:0030057 desmosome Database 0.26
Category members GO Category GO:0005882 intermediate filament Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007155 cell adhesion Database 0


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