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Query: PLEKHG2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLEKHG2 0 -0.834 0.720 -1.130

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLEKHG2 Phosphorylation S482 -0.019 -0.815 _RQS(ph)EPVKDPYVM(ox)FPQNAK_
PLEKHG2 Phosphorylation S610 -1.029 _GPS(ph)PLHVLEGLESSIAAEMPSIPCLTK_
PLEKHG2 Phosphorylation T1257 -1.223 _LESSDLT(ph)PPHS(ph)PPPSSR_
PLEKHG2 Phosphorylation S1261 -1.223 _LESSDLT(ph)PPHS(ph)PPPSSR_

Background Information for PLEKHG2:


Pubmed-PLEKHG2 »
Uniprot-PLEKHG2 »
Biogrid-PLEKHG2 »
ProteomicsDB-PLEKHG2 »

Tumorportal-PLEKHG2 »
COSMIC-PLEKHG2 »
GenomeRNAi-PLEKHG2 »
Genecards-PLEKHG2


Protein-protein Interactions for PLEKHG2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in PLEKHG2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members DH-domain IPR000219 0.05


Protein complexes (CORUM database) featuring PLEKHG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLEKHG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_221 REACTOME_SIGNALLING_BY_NGF 0 2.14
Category members Pathway Pathway_243 REACTOME_GPCR_DOWNSTREAM_SIGNALING 0 1.27
Category members Pathway Pathway_256 REACTOME_SIGNALING_BY_GPCR 0 0.83
Category members GO Category GO:0048011 neurotrophin TRK receptor signaling pathway Database 0.63
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0051056 regulation of small GTPase mediated signal transduction Database 0.25
Category members Pathway Pathway_739 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 0 0.23
Category members Pathway Pathway_779 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 0 0.2
Category members GO Category GO:0035023 regulation of Rho protein signal transduction Database 0.17
Category members Pathway Pathway_1140 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK 0 0.1
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members Pathway Pathway_519 REACTOME_SIGNALING_BY_RHO_GTPASES 0 0
Category members Pathway Pathway_623 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS 0 0


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