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Query: PKM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PKM 0 2.690 1.170 -0.120 0.017 1.398 -1.294 0.074 -0.041

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PKM Ubiquitylation K498 -0.348 1.499 _VNFAMNVGK(gl)AR_
PKM Ubiquitylation K66 0.692 1.175 _EMIK(gl)SGMNVAR_
PKM Ubiquitylation K136 1.129 _GSGTAEVELKK(gl)_
PKM Ubiquitylation K207 0.653 1.108 _GADFLVTEVENGGSLGSKK(gl)_
PKM Ubiquitylation K206 0.325 0.965 _GADFLVTEVENGGSLGSK(gl)K_
PKM Ubiquitylation K166 0.555 0.929 _NICK(gl)VVEVGSK_
PKM Ubiquitylation K322 0.128 0.502 _AGK(gl)PVICATQMLESMIK_
PKM Ubiquitylation K433 0.399 _CCSGAIIVLTK(gl)SGR_
PKM Ubiquitylation K62 0.782 0.248 _SVETLK(gl)EMIK_
PKM Ubiquitylation K311 0.807 0.083 _VFLAQK(gl)MMIGR_
PKM Phosphorylation S37 -0.098 0.015 _LDIDS(ph)PPITAR_
PKM Ubiquitylation K305 -0.028 -0.012 _GDLGIEIPAEK(gl)VFLAQK_
PKM Ubiquitylation K270 0.863 -0.154 _IISK(gl)IENHEGVR_
PKM Ubiquitylation K266 1.003 -0.378 _GKNIK(gl)IISK_
PKM Ubiquitylation K135 0.397 _GSGTAEVELK(gl)K_
PKM Ubiquitylation K141 1.121 _GATLK(gl)ITLDNAYMEK_

Background Information for PKM:


Pubmed-PKM »
Uniprot-PKM »
Biogrid-PKM »
ProteomicsDB-PKM »

Tumorportal-PKM »
COSMIC-PKM »
GenomeRNAi-PKM »
Genecards-PKM


Protein-protein Interactions for PKM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC88A Cat. description Hein, Mann, Cell 2015
Category members IP bait COBLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PKM Cat. description Hein, Mann, Cell 2015


Protein Domains in PKM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pyr_Knase IPR001697 0.22
Category members Pyrv_Knase_brl IPR015793 0.22
Category members Pyrv_Knase_C IPR015795 0.22
Category members Pyrv_Knase-like_insert_dom IPR011037 0.21
Category members Pyrv/PenolPyrv_Kinase-like_dom IPR015813 0.03


Protein complexes (CORUM database) featuring PKM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PKM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0004743 pyruvate kinase activity Database 0.22
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0012501 programmed cell death Database 0.1
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0030955 potassium ion binding Database 0


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