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Query: PIP4K2A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PIP4K2A 0 0.626 -0.860 0.890 -0.003

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PIP4K2A Ubiquitylation K395 0.518 -0.779 _HGAGAEISTVNPEQYSK(gl)R_

Background Information for PIP4K2A:


Pubmed-PIP4K2A »
Uniprot-PIP4K2A »
Biogrid-PIP4K2A »
ProteomicsDB-PIP4K2A »

Tumorportal-PIP4K2A »
COSMIC-PIP4K2A »
GenomeRNAi-PIP4K2A »
Genecards-PIP4K2A


Protein-protein Interactions for PIP4K2A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PIP4K2C Cat. description Hein, Mann, Cell 2015
Category members IP bait ARHGAP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARL6IP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EAF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST6GAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM194A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF428 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRANB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PIP4K2A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PInositol-4-P-5-kinase_core IPR002498 0
Category members PInositol-4P-5-kinase_core_sub IPR016034 0


Protein complexes (CORUM database) featuring PIP4K2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PIP4K2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_106 KEGG_INOSITOL_PHOSPHATE_METABOLISM 0 0.28
Category members Disease phenotype Precursor_B-cell_acute_lymphoblastic_leukemia Precursor B-cell acute lymphoblastic leukemia Database 0.25
Category members GO Category GO:0016310 phosphorylation Database 0.21
Category members Pathway Pathway_580 KEGG_REGULATION_OF_ACTIN_CYTOSKELETON 0 0.08
Category members GO Category GO:0006661 phosphatidylinositol biosynthetic process Database 0.06
Category members GO Category GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity Database 0.04
Category members Pathway Pathway_103 REACTOME_PI_METABOLISM 0 0.04
Category members GO Category GO:0035855 megakaryocyte development Database 0.02
Category members Pathway Pathway_100 REACTOME_PHOSPHOLIPID_METABOLISM 0 0
Category members Pathway Pathway_102 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_488 KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM 0 0
Category members GO Category GO:0005575 cellular_component Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0016307 phosphatidylinositol phosphate kinase activity Database 0
Category members GO Category GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity Database 0
Category members GO Category GO:0046488 phosphatidylinositol metabolic process Database 0


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