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Query: PFDN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PFDN1 0 1.687 0.040 -0.360

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PFDN1 Ubiquitylation K10 0.055 0.702 _(ac)AAPVDLELK(gl)K_
PFDN1 Ubiquitylation K11 0.290 0.616 _K(gl)AFTELQAK_
PFDN1 Ubiquitylation K28 0.985 _VK(gl)LADIQIEQLNR_
PFDN1 Ubiquitylation K97 -0.053 _IKELEQK(gl)K_
PFDN1 Ubiquitylation K106 0.479 _SVK(gl)EAEDNIR_

Background Information for PFDN1:





Protein-protein Interactions for PFDN1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF21A Cat. description Hein, Mann, Cell 2015
Category members IP bait PFDN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RFWD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait VBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR61 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCAF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GNB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKAG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PFDN1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PFD_beta-like IPR002777 0.31
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring PFDN1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 112 Prefoldin complex Database 0.27
Category members Corum 33 Prefoldin Database 0.27


Categories featuring PFDN1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members Pathway Pathway_742 REACTOME_PROTEIN_FOLDING 0 0.9
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members GO Category GO:0051084 'de novo' posttranslational protein folding Database 0.63
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members Pathway Pathway_1288 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC 0 0.4
Category members GO Category GO:0016272 prefoldin complex Database 0.15
Category members GO Category GO:0021549 cerebellum development Database 0.14
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0021537 telencephalon development Database 0
Category members GO Category GO:0042113 B cell activation Database 0


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